15. Ulusal Dahili ve Cerrahi Bilimler Yoğun Bakım Kongresi

7. Avrasya Yoğun Bakım Toplantısı


 
ANTIBIOTIC RESISTANCE OF ACINETOBACTER STRAINS IN OUR INTENSIVE CARE UNIT : A RETROSPECTIVE STUDY
EBRU KARAKOÇ 1 AYŞE AYYILDIZ 1 BİRGÜL YELKEN 1

1- ESKİŞEHİR OSMANGAZİ ÜNİVERSİTESİ TIP FAKÜLTESİ ANESTEZİYOLOJİ VE REANİMASYON ANABİLİM DALI
 
Özet:

 BACKGROUND:Antibiotic resistance development in the treatment of acinetobacter infection is a serious health care problem and responsible for high mortality in intensive care.It is important to identify endemic antibiotic resistance spectrum to beat this pathogen.(1)In our study, it was aimed to determine rates of resistance of Acinetobacter strains isolated from various samples in our intensive care.

METHOTS:We examined the records of acinetobacter isolates  and antibiotics resistance for one year follewed up in our ICU.The samples from different patients and different type of samples of the same patients were evaluated.The data was analyzed with SPSS for Windows version 23.0. Categorical variables were expressed in terms of numbers and percentage.

RESULTS:50% of the samples were isolated from tracheostomy.96.4% of the 138 isolates were A. Baumanii and 3.6% were the other strains.We found high resistance to all of antibiotics except cholistin(3.6%) and tigecycline (13.1%).

 

Antibiogram

Susceptible

Intermediate susceptibility

Resistant

Amikacin

43 (31,2%)

14 (10,1%)

81 (58,7%)

Ciprofloxacin

3 (2,2%)

-

135 (97,8%)

Cholistin

133 (96,4%)

-

5 (3,6%)

Gentamicin

67 (48,9%)

-

70 (51,1%)

Imipenem

4 (3,4%)

13 (11,1%)

100 (85,5%)

Levofloxacin

1 (0,9%)

-

114 (99,1%)

Meropenem

1 (0,7%)

-

137 (99,3%)

Tigecycline

68 (68,7%)

18 (18,2%)

13 (13,1%)

Trimethoprim/Sulfamethoxazole

39 (28,3%)

-

99 (71,7%)

Tobramycin

53 (43,1%)

-

70 (56,9%)

 

 

Amicasin

Ciprofloxacin

Cholistin

Gentamicin

Imipenem

Levofloxacin

Meropenem

Tigecycline

Trimethoprim/

sulfamethoxazole

Tobramycin

Material

                   
 

Tracheostomy

43 (62,3%)

67 (97,1%)

3 (4,3%)

44 (63,8%)

53 (89,8%)

57 (100%)

69 (100%)

6 (11,5%)

52 (75,4%)

39 (66,1%)

 

Nasogastric tube

10 (71,4%)

14 (100%)

-

8 (57,1%)

8 (72,7%)

11 (91,7%)

14 (100%)

2 (22,2%)

9 (64,3%)

7 (58,3%)

 

Blood

11 (57,9%)

18 (94,7%)

-

4 (21,1%)

13 (86,7%)

15 (100%)

18 (94,7%)

1 (7,7%)

11 (57,9%)

8 (44,4%)

 

Urine

4 (50%)

8 (100%)

-

4 (50%)

7 (87,5%)

8 (100%)

8 (100%)

-

7 (87,5%)

4 (50%)

 

Ascites

6 (50%)

12 (100%)

2 (16,7%)

5 (45,5%)

8 (66,7%)

11 (100%)

12 (100%)

3 (50%)

10 (83,3%)

6 (50%)

 

Intubation tube

2 (100%)

2 (100%)

-

1 (50%)

-

-

2 (100%)

-

2 (100%)

1 (100%)

 

Sputum

1 (100%)

1 (100%)

-

-

-

-

1 (100%)

-

1 (100%)

1 (100%)

 

Wound

1 (14,3%)

7 (100%)

-

4 (57,1%)

6 (100%)

6 (100%)

7 (100%)

-

5 (71,4%)

3 (50%)

 

Other

3 (50%)

6 (100%)

-

-

5 (83,3%)